Icariin plus curcumol enhances autophagy through the mTOR pathway and promotes cathepsin B-mediated pyroptosis of prostate cancer cells

Icariin plus curcumol enhances autophagy through the mTOR pathway and promotes cathepsin B-mediated pyroptosis of prostate cancer cells

Objective: To examine the effect of icariin plus curcumol on prostate cancer cells PC3 and elucidate the underlying mechanisms. Methods: We employed the Cell Counting Kit 8 assay and colony formation assay to assess cell viability and proliferation. Autophagy expression was analyzed using monodansyl...

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Bibliographic Details
Main Authors: Xu-Yun Wang, Wen-Jing Xu, Bo-Nan Li, Tian-Song Sun, Wen Sheng
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
icariin; curcumol; autophagy; mtor; cathepsin b; pyroptosis; prostate cancer
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2024;volume=14;issue=2;spage=55;epage=64;aulast=Wang

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2024;volume=14;issue=2;spage=55;epage=64;aulast=Wang

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