Genetically determined hypercholesterolemia in a rhesus monkey family due to a deficiency of the LDL receptor.

A family of rhesus monkeys comprising a sire, a dam, and four male offspring were fed a cholesterol-free Purina Chow diet for several months. The sire, 431-J, and two of the offspring, B-8204 and B-8806, had persistent plasma cholesterol levels in the range of 100-130 mg/dl, whereas the dam, 766-I,...

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Bibliographic Details
Main Authors: A M Scanu, A Khalil, L Neven, M Tidore, G Dawson, D Pfaffinger, E Jackson, K D Carey, H C McGill, G M Fless
Format: Article
Language:English
Published: Elsevier 1988-12-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520384157