Microsatellite instability and mismatch repair protein deficiency: equal predictive markers?

Current clinical guidelines recommend mismatch repair (MMR) protein immunohistochemistry (IHC) or molecular microsatellite instability (MSI) tests as predictive markers of immunotherapies. Most of the pathological guidelines consider MMR protein IHC as the gold standard test to identify cancers with...

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Bibliographic Details
Main Authors: Maja L. Nádorvári, Gábor Lotz, Janina Kulka, András Kiss, József Tímár
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Pathology and Oncology Research
Subjects:
Online Access:https://www.por-journal.com/articles/10.3389/pore.2024.1611719/full