Comparison of Experimental Approaches Used to Determine the Structure and Function of the Class D G Protein-Coupled Yeast α-Factor Receptor

The <i>Saccharomyces cerevisiae</i> α-factor mating pheromone receptor (Ste2p) has been studied as a model for the large medically important family of G protein-coupled receptors. Diverse yeast genetic screens and high-throughput mutagenesis of <i>STE2</i> identified a large...

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Bibliographic Details
Main Authors: Mark E. Dumont, James B. Konopka
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/6/761