PLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2 and synapsin III

Abstract Dopamine neurons are essential for voluntary movement, reward learning, and motivation, and their dysfunction is closely linked to various psychological and neurodegenerative diseases. Hence, understanding the detailed signaling mechanisms that functionally modulate dopamine neurons is cruc...

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Bibliographic Details
Main Authors: Hye Yun Kim, Jieun Lee, Hyun-Jin Kim, Byeong Eun Lee, Jaewook Jeong, Eun Jeong Cho, Hyun-Jun Jang, Kyeong Jin Shin, Min Ji Kim, Young Chan Chae, Seung Eun Lee, Kyungjae Myung, Ja-Hyun Baik, Pann-Ghill Suh, Jae-Ick Kim
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01104-y