Gandouling alleviates nerve injury through PI3K/Akt/FoxO1 and Sirt1/FoxO1 signaling pathway to inhibit autophagy in the rats model of Wilson's disease

Abstract Introduction Previous studies have shown that Gandouling (GDL) may alleviate the nerve damage caused by Wilson's disease (WD) by inhibiting the autophagy of nerve cell mitochondria. However, its mechanisms are still unclear. Revealing the therapeutic mechanism of GDL is beneficial for...

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Bibliographic Details
Main Authors: Li Chen, Wangyang Xu, Yuting Zhang, Hao Chen, Yanquan Han
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Brain and Behavior
Subjects:
Online Access:https://doi.org/10.1002/brb3.3325