Misregulated E-cadherin expression associated with an aggressive brain tumor phenotype.

Cadherins are essential components of the adherens junction complexes that mediate cell-cell adhesion and regulate cell motility. During tissue morphogenesis, changes in cadherin expression (known as cadherin switching) are a common mechanism for altering cell fate. Cadherin switching is also common...

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Bibliographic Details
Main Authors: Laura J Lewis-Tuffin, Fausto Rodriguez, Caterina Giannini, Bernd Scheithauer, Brian M Necela, Jann N Sarkaria, Panos Z Anastasiadis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2965143?pdf=render