Immune cell-derived extracellular vesicular microRNAs induce pancreatic beta cell apoptosis

Immune cell-derived extracellular vesicular microRNAs induce pancreatic beta cell apoptosis

Background: Type 1 diabetes mellitus (T1DM) is an autoimmune disease caused by an autoimmune response against pancreatic islet β cells. Increasing evidence indicates that specific microRNAs (miRNAs) from immune cells extracellular vesicles are involved in islet β cells apoptosis. Methods: In this st...

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Bibliographic Details
Main Authors: Yueyang Yu, Mengyin Li, Yuxuan Zhao, Fangzhou Fan, Wenxiang Wu, Yuhua Gao, Chunyu Bai
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Type 1 diabetes mellitus
Immune cells
Extracellular vesicles
miRNA
β cells
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022032832

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http://www.sciencedirect.com/science/article/pii/S2405844022032832

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