Antitumor Activity and Mechanism of Action of the Antimicrobial Peptide AMP-17 on Human Leukemia K562 Cells

Antitumor Activity and Mechanism of Action of the Antimicrobial Peptide AMP-17 on Human Leukemia K562 Cells

Cancer is one of the most common malignant diseases in the world. Hence, there is an urgent need to search for novel drugs with antitumor activity against cancer cells. AMP-17, a natural antimicrobial peptide derived from <i>Musca domestica</i>, has antimicrobial activity against Gram-po...

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Bibliographic Details
Main Authors: Zhuqing Tian, Longbing Yang, Mingjiao Huang, Chaoqin Sun, Mingming Chen, Wenjing Zhao, Jian Peng, Guo Guo
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
antimicrobial peptides
AMP-17
human leukemia K562 cells
anti-tumor
membrane-disruption
apoptosis
Online Access:https://www.mdpi.com/1420-3049/27/22/8109

Internet

https://www.mdpi.com/1420-3049/27/22/8109

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