Silencing of TGFβ signalling in microglia results in impaired homeostasis

Silencing of TGFβ signalling in microglia results in impaired homeostasis

While previous studies had shown the requirement of TGFβ signalling in microglia gene expression, the specificity of the loss-of-function was unclear. Here, Zöller and colleagues generate microglia specific cKO of TGFβ receptor 2, and show dispensable function of Tgfbr2 in microglial survival and th...

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Bibliographic Details
Main Authors: Tanja Zöller, Artur Schneider, Christian Kleimeyer, Takahiro Masuda, Phani Sankar Potru, Dietmar Pfeifer, Thomas Blank, Marco Prinz, Björn Spittau
Format: Article
Language:English
Published: Nature Portfolio 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06224-y

Internet

https://doi.org/10.1038/s41467-018-06224-y

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