Regulation of platelet membrane protein shedding in health and disease
Extracellular proteolysis of platelet plasma membrane proteins is an event that ensues platelet activation. Shedding of surface receptors such as glycoprotein (GP) Ibα, GPV and GPVI as well as externalized proteins P-selectin and CD40L releases soluble ectodomain fragments that are subsequently dete...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2017-05-01
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Series: | Platelets |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/09537104.2016.1203401 |