Formulation and in vitro evaluation of Eudragit S-100 coated naproxen matrix tablets for colon-targeted drug delivery system

Formulation and in vitro evaluation of Eudragit S-100 coated naproxen matrix tablets for colon-targeted drug delivery system

The purpose of the present investigation was to prepare matrix tablets of naproxen using a hydrophobic polymer, i.e., Eudragit RLPO, RSPO, and combination of both, by wet granulation method. The tablets were further coated with different concentrations of Eudragit S-100, a pH-sensitive polymer, by d...

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Bibliographic Details
Main Authors: Rohit Mehta, Anuj Chawla, Pooja Sharma, Pravin Pawar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Eudragit S-100
matrix tablets
naproxen
non-Fickian
rat cecal
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2013;volume=4;issue=1;spage=31;epage=41;aulast=Mehta

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http://www.japtr.org/article.asp?issn=2231-4040;year=2013;volume=4;issue=1;spage=31;epage=41;aulast=Mehta

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