Formulation Development and In Vitro/In Vivo Characterization of Methotrexate-Loaded Nanoemulsion Gel Formulations for Enhanced Topical Delivery

Formulation Development and In Vitro/In Vivo Characterization of Methotrexate-Loaded Nanoemulsion Gel Formulations for Enhanced Topical Delivery

Methotrexate-loaded oil-in-water nanoemulsion formulations were prepared using the high shear homogenization technique. A drug excipient study (ATR-FTIR) was carried out to investigate the compatibility between the drug, the polymers, and its admixtures. The thermal stability of the nanoemulsion for...

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Bibliographic Details
Main Authors: Muhammad Shahid Latif, Asif Nawaz, Mufarreh Asmari, Jalal Uddin, Hidayat Ullah, Saeed Ahmad
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Gels
Subjects:
methotrexate
nanoemulsion gel
olive oil
almond oil
clove oil
chitosan
Online Access:https://www.mdpi.com/2310-2861/9/1/3

Internet

https://www.mdpi.com/2310-2861/9/1/3

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