Determinação simultânea de resíduos de sulfametoxazol e trimetoprima em superfícies de equipamentos de produção Simultaneous determination of sulfamethoxazole and trimethoprim residues on manufacturing equipment surfaces

<abstract language="eng">A cleaning validation method was developed and validated, based on swabbing sampling and simultaneous chromatographic determination of sulfamethoxazole (SMX) and trimethoprim (TMP) residues. The method presented limits of detection of 0.06 mg mL-1 for SMX and...

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Bibliographic Details
Main Authors: Roberto C. Coutinho, Elder T. Barbosa, Marcelo M. Sena, Caridad Noda Pérez
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2009-01-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000800038