IL-22 protects against liver pathology and lethality of an experimental blood-stage malaria infection

IL-22 protects against liver pathology and lethality of an experimental blood-stage malaria infection

The host response following malaria infection depends on a fine balance between levels of pro-inflammatory and anti-inflammatory mediators resulting in the resolution of the infection or immune-mediated pathology. Whilst other components of the innate immune system contribute to the pro-inflammatory...

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Bibliographic Details
Main Authors: Beatris eMastelic, Ana Paula eFreitas do Rosario, Marc eVeldhoen, Jean-Christophe eRenauld, William eJarra, Anne-Marit eSponaas, Sophie eRoetynck, Brigitta eStockinger, Jean eLanghorne
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Immunology
Subjects:
Malaria
Plasmodium chabaudi
IL-17
IL-22
Th17
liver damage
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00085/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00085/full

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