SCFRMF mediates degradation of the meiosis-specific recombinase DMC1

SCFRMF mediates degradation of the meiosis-specific recombinase DMC1

Abstract Meiotic recombination requires the specific RecA homolog DMC1 recombinase to stabilize strand exchange intermediates in most eukaryotes. Normal DMC1 levels are crucial for its function, yet the regulatory mechanisms of DMC1 stability are unknown in any organism. Here, we show that the degra...

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Bibliographic Details
Main Authors: Wanyue Xu, Yue Yu, Juli Jing, Zhen Wu, Xumin Zhang, Chenjiang You, Hong Ma, Gregory P. Copenhaver, Yan He, Yingxiang Wang
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40799-5

Internet

https://doi.org/10.1038/s41467-023-40799-5

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