Regulation of Fibroblast Activation Protein by Transforming Growth Factor Beta-1 in Glioblastoma Microenvironment

Regulation of Fibroblast Activation Protein by Transforming Growth Factor Beta-1 in Glioblastoma Microenvironment

The proline-specific serine protease fibroblast activation protein (FAP) can participate in the progression of malignant tumors and represents a potential diagnostic and therapeutic target. Recently, we demonstrated an increased expression of FAP in glioblastomas, particularly those of the mesenchym...

Full description

Bibliographic Details
Main Authors: Evzen Krepela, Zdislava Vanickova, Petr Hrabal, Michal Zubal, Barbora Chmielova, Eva Balaziova, Petr Vymola, Ivana Matrasova, Petr Busek, Aleksi Sedo
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma
tumor microenvironment
transforming growth factor beta
fibroblast activation protein
seprase
regulation of expression
Online Access:https://www.mdpi.com/1422-0067/22/3/1046

Internet

https://www.mdpi.com/1422-0067/22/3/1046

Similar Items