FDG-PET hypermetabolism is associated with higher tau-PET in mild cognitive impairment at low amyloid-PET levels

FDG-PET hypermetabolism is associated with higher tau-PET in mild cognitive impairment at low amyloid-PET levels

Abstract Background FDG-PET hypermetabolism can be observed in mild cognitive impairment (MCI), but the link to primary pathologies of Alzheimer’s diseases (AD) including amyloid and tau is unclear. Methods Using voxel-based regression, we assessed local interactions between amyloid- and tau-PET on...

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Bibliographic Details
Main Authors: Anna Rubinski, Nicolai Franzmeier, Julia Neitzel, Michael Ewers, the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Alzheimer’s Research & Therapy
Subjects:
FDG-PET
Hypermetabolism
Tau-PET
Amyloid-PET
Hyperactivation
Mild cognitive impairment
Online Access:http://link.springer.com/article/10.1186/s13195-020-00702-6

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http://link.springer.com/article/10.1186/s13195-020-00702-6

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