Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes[S]

Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes[S]

Peroxisome proliferator-activated receptor-α (PPARα) is a dietary lipid sensor, whose activation results in hypolipidemic effects. In this study, we investigated whether PPARα activation affects energy metabolism in white adipose tissue (WAT). Activation of PPARα by its agonist (bezafibrate) markedl...

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Bibliographic Details
Main Authors: Tsuyoshi Goto, Joo-Young Lee, Aki Teraminami, Yong-Il Kim, Shizuka Hirai, Taku Uemura, Hiroyasu Inoue, Nobuyuki Takahashi, Teruo Kawada
Format: Article
Language:English
Published: Elsevier 2011-05-01
Series:Journal of Lipid Research
Subjects:
PPARα
adipocyte differentiation
insulin resistance
metabolic syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408740

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520408740

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