A Riboswitch-Driven Era of New Antibacterials

A Riboswitch-Driven Era of New Antibacterials

Riboswitches are structured non-coding RNAs found in the 5′ UTR of important genes for bacterial metabolism, virulence and survival. Upon the binding of specific ligands that can vary from simple ions to complex molecules such as nucleotides and tRNAs, riboswitches change their local and global mRNA...

Full description

Bibliographic Details
Main Authors: Nikoleta Giarimoglou, Adamantia Kouvela, Alexandros Maniatis, Athanasios Papakyriakou, Jinwei Zhang, Vassiliki Stamatopoulou, Constantinos Stathopoulos
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Antibiotics
Subjects:
riboswitch
antibiotics
antibacterial drug targets
RNA
Online Access:https://www.mdpi.com/2079-6382/11/9/1243

Internet

https://www.mdpi.com/2079-6382/11/9/1243

Similar Items