Endothelial caveolin-1 regulates cerebral thrombo-inflammation in acute ischemia/reperfusion injury

Endothelial caveolin-1 regulates cerebral thrombo-inflammation in acute ischemia/reperfusion injury

Summary: Background: Thrombo-inflammation is an important checkpoint that orchestrates infarct development in ischemic stroke. However, the underlying mechanism remains largely unknown. Here, we explored the role of endothelial Caveolin-1 (Cav-1) in cerebral thrombo-inflammation. Methods: The corre...

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Bibliographic Details
Main Authors: Xiaohao Zhang, Pengyu Gong, Ying Zhao, Ting Wan, Kang Yuan, Yunyun Xiong, Min Wu, Mingming Zha, Yunzi Li, Teng Jiang, Xinfeng Liu, Ruidong Ye, Yi Xie, Gelin Xu
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:EBioMedicine
Subjects:
Caveolin-1
Inflammation
Ischemic stroke
Microthrombosis
Vascular endothelium
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422004571

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http://www.sciencedirect.com/science/article/pii/S2352396422004571

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