Overexpressed GATA3 enhances the sensitivity of colorectal cancer cells to oxaliplatin through regulating MiR-29b

Overexpressed GATA3 enhances the sensitivity of colorectal cancer cells to oxaliplatin through regulating MiR-29b

Abstract Background GATA binding protein 3 (GATA3) and miR-29b are related to colorectal cancer (CRC). The current study explored the regulatory relationship between GATA3 and miR-29b, and the mechanism of the two in the drug resistance of CRC cells to oxaliplatin. Method Apoptosis of CRC cells indu...

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Bibliographic Details
Main Authors: Wei Wang, Mei Wang, Jing Xu, Fei Long, Xianbao Zhan
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Cancer Cell International
Subjects:
Colorectal cancer
Oxaliplatin
GATA binding protein 3 (GATA3)
miR-29b
Online Access:http://link.springer.com/article/10.1186/s12935-020-01424-3

Internet

http://link.springer.com/article/10.1186/s12935-020-01424-3

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