Pyruvate kinase M2 regulates mitochondrial homeostasis in cisplatin-induced acute kidney injury

Pyruvate kinase M2 regulates mitochondrial homeostasis in cisplatin-induced acute kidney injury

Abstract An important pathophysiological process of acute kidney injury (AKI) is mitochondrial fragmentation in renal tubular epithelial cells, which leads to cell death. Pyruvate kinase M2 (PKM2) is an active protein with various biological functions that participates in regulating glycolysis and p...

Full description

Bibliographic Details
Main Authors: Wenjia Xie, Qingyun He, Yan Zhang, Xinxin Xu, Ping Wen, Hongdi Cao, Yang Zhou, Jing Luo, Junwei Yang, Lei Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06195-z

Internet

https://doi.org/10.1038/s41419-023-06195-z

Similar Items