Synthesis and Antiparasitic Activity of New Trithiolato-Bridged Dinuclear Ruthenium(II)-arene-carbohydrate Conjugates

Synthesis and Antiparasitic Activity of New Trithiolato-Bridged Dinuclear Ruthenium(II)-arene-carbohydrate Conjugates

Eight novel carbohydrate-tethered trithiolato dinuclear ruthenium(II)-arene complexes were synthesized using CuAAC ‘click’ (Cu(I)-catalyzed azide-alkyne cycloaddition) reactions, and there in vitro activity against transgenic <i>T. gondii</i> tachyzoites constitutively expressing β-galac...

Full description

Bibliographic Details
Main Authors: Isabelle Holzer, Oksana Desiatkina, Nicoleta Anghel, Serena K. Johns, Ghalia Boubaker, Andrew Hemphill, Julien Furrer, Emilia Păunescu
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
ruthenium(II)-arene complexes
bioorganometallic
carbohydrates
CuAAC reactions
antiparasitic
<i>Toxoplasma gondii</i>
Online Access:https://www.mdpi.com/1420-3049/28/2/902

Internet

https://www.mdpi.com/1420-3049/28/2/902

Similar Items