Live-Cell Imaging of Physiologically Relevant Metal Ions Using Genetically Encoded FRET-Based Probes

Live-Cell Imaging of Physiologically Relevant Metal Ions Using Genetically Encoded FRET-Based Probes

Essential biochemical reactions and processes within living organisms are coupled to subcellular fluctuations of metal ions. Disturbances in cellular metal ion homeostasis are frequently associated with pathological alterations, including neurotoxicity causing neurodegeneration, as well as metabolic...

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Bibliographic Details
Main Authors: Helmut Bischof, Sandra Burgstaller, Markus Waldeck-Weiermair, Thomas Rauter, Maximilian Schinagl, Jeta Ramadani-Muja, Wolfgang F. Graier, Roland Malli
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
FRET
fluorescent protein
FP
fluorescence microscopy
genetically encoded probes
imaging
Ca<sup>2+</sup>
Cu<sup>+</sup>
Cu<sup>2+</sup>
Fe<sup>2+</sup>
Fe<sup>3+</sup>
K<sup>+</sup>
Mg<sup>2+</sup>
Mn<sup>2+</sup>
Zn<sup>2+</sup>
Online Access:https://www.mdpi.com/2073-4409/8/5/492

Internet

https://www.mdpi.com/2073-4409/8/5/492

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