Contribution of stochastic partitioning at human embryonic stem cell division to NANOG heterogeneity.

Heterogeneity is an often unappreciated characteristic of stem cell populations yet its importance in fate determination is becoming increasingly evident. Although gene expression noise has received greater attention as a source of non-genetic heterogeneity, the effects of stochastic partitioning of...

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Bibliographic Details
Main Authors: Jincheng Wu, Emmanuel S Tzanakakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511357?pdf=render