YAP promotes autophagy and progression of gliomas via upregulating HMGB1

YAP promotes autophagy and progression of gliomas via upregulating HMGB1

Abstract Background Due to the hypoxia and nutrient deficiency microenvironment, glioblastoma (GBM) exhibits high autophagy activity and autophagy plays an important role in the progression of GBM. However, the molecular mechanism of autophagy in GBM progression remains unclear. The aim of this stud...

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Bibliographic Details
Main Authors: Min Zhao, Yu Zhang, Yang Jiang, Kai Wang, Xiang Wang, Ding Zhou, Yan Wang, Rutong Yu, Xiuping Zhou
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Glioma
YAP
Autophagy
HMGB1
Progression
Online Access:https://doi.org/10.1186/s13046-021-01897-8

Internet

https://doi.org/10.1186/s13046-021-01897-8

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