Melatonin Prevents T Lymphocyte Infiltration to the Kidneys of Hypertensive Rats, Induced by a High-Salt Diet, by Preventing the Expression of CXCR3 Ligand Chemokines

In a previous study, we demonstrated that melatonin prevents kidney damage in a salt-induced hypertension model by decreasing oxidative stress. We hypothesized that this effect involves melatonin’s immunomodulatory properties. In vivo Study-Dahl salt-sensitive (DSS) rats were fed normal chow, a high...

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Bibliographic Details
Main Authors: Ariel Bier, Rawan Khashab, Yehonatan Sharabi, Ehud Grossman, Avshalom Leibowitz
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/13/10/3577