Predicted neoantigen load in non-hypermutated endometrial cancers: Correlation with outcome and tumor-specific genomic alterations

Elevated neoantigen load has been previously correlated with improved outcome and response to immune checkpoint blockade in various tumor types. In endometrial cancer, previous studies of neoantigen load prediction have shown that the hypermutated MSI and POLE-mutated tumors harbor significantly hig...

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Bibliographic Details
Main Authors: Sachet A. Shukla, Brooke E. Howitt, Catherine J. Wu, Panagiotis A. Konstantinopoulos
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Gynecologic Oncology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578916300947