Chronic Voluntary Ethanol Consumption Induces Favorable Ceramide Profiles in Selectively Bred Alcohol-Preferring (P) Rats.

Heavy alcohol consumption has detrimental neurologic effects, inducing widespread neuronal loss in both fetuses and adults. One proposed mechanism of ethanol-induced cell loss with sufficient exposure is an elevation in concentrations of bioactive lipids that mediate apoptosis, including the membran...

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Bibliographic Details
Main Authors: Jessica Godfrey, Lisa Jeanguenin, Norma Castro, Jeffrey J Olney, Jason Dudley, Joseph Pipkin, Stanley M Walls, Wei Wang, Deron R Herr, Greg L Harris, Susan M Brasser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4583526?pdf=render