Random Mutational Analysis Targeting Residue K<sup>155</sup> within the Transmembrane β-Hairpin of the Mosquitocidal Mpp46Ab Toxin

Mpp46Ab is a mosquito-larvicidal pore-forming toxin derived from <i>Bacillus thuringiensis</i> TK-E6. Pore formation is believed to be a central mode of Mpp46Ab action, and the cation selectivity of the channel pores, in particular, is closely related to its mosquito-larvicidal activity....

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Bibliographic Details
Main Authors: Midoka Miyazaki, Mami Asakura, Toru Ide, Tohru Hayakawa
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/12/12/1481