Structure and dynamics of endogenous cardiac troponin complex in human heart tissue captured by native nanoproteomics

Abstract Protein complexes are highly dynamic entities that display substantial diversity in their assembly, post-translational modifications, and non-covalent interactions, allowing them to play critical roles in various biological processes. The heterogeneity, dynamic nature, and low abundance of...

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Bibliografiska uppgifter
Huvudupphovsmän: Emily A. Chapman, David S. Roberts, Timothy N. Tiambeng, Jãán Andrews, Man-Di Wang, Emily A. Reasoner, Jake A. Melby, Brad H. Li, Donguk Kim, Andrew J. Alpert, Song Jin, Ying Ge
Materialtyp: Artikel
Språk:English
Publicerad: Nature Portfolio 2023-12-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/s41467-023-43321-z