Finite Element-Based Personalized Simulation of Duodenal Hydrogel Spacer: Spacer Location Dependent Duodenal Sparing and a Decision Support System for Spacer-Enabled Pancreatic Cancer Radiation Therapy

PurposePancreatic cancer is the fourth leading cause of cancer-related death, with a very low 5-year overall survival rate (OS). Radiation therapy (RT) together with dose escalation significantly increases the OS at 2 and 3 years. However, dose escalation is very limited due to the proximity of the...

Full description

Bibliographic Details
Main Authors: Hamed Hooshangnejad, Sina Youssefian, Amol Narang, Eun Ji Shin, Avani Dholakia Rao, Sarah Han-Oh, Todd McNutt, Junghoon Lee, Chen Hu, John Wong, Kai Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.833231/full