Cas14a1-Mediated Nucleic Acid Diagnostics for Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) is the main genetic cause of infant death. In >95% of the patients with SMA, the disease is caused by a single hotspot pathogenic mutation: homozygous deletion of exon 7 of the survival motor neuron 1 gene (<i>SMN1</i>). Recently, clustered regularly inte...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-04-01
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Series: | Biosensors |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-6374/12/5/268 |