HIV-1 Tat Binding to PCAF Bromodomain: Structural Determinants from Computational Methods
The binding between the HIV-1 trans-activator of transcription (Tat) and p300/(CREB-binding protein)-associated factor (PCAF) bromodomain is a crucial step in the HIV-1 life cycle. However, the structure of the full length acetylated Tat bound to PCAF has not been yet determined experimentally. Acet...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-08-01
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Series: | Biology |
Subjects: | |
Online Access: | http://www.mdpi.com/2079-7737/1/2/277 |