An analytical framework for decoding cell type-specific genetic variation of gene regulation

An analytical framework for decoding cell type-specific genetic variation of gene regulation

Abstract A deeper understanding of genetic regulation and functional mechanisms underlying genetic associations with complex traits and diseases is impeded by cellular heterogeneity and linkage disequilibrium. To address these limits, we introduce Huatuo, a framework to decode genetic variation of g...

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Bibliographic Details
Main Authors: Yanyu Xiao, Jingjing Wang, Jiaqi Li, Peijing Zhang, Jingyu Li, Yincong Zhou, Qing Zhou, Ming Chen, Xin Sheng, Zhihong Liu, Xiaoping Han, Guoji Guo
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39538-7

Internet

https://doi.org/10.1038/s41467-023-39538-7

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