Expression of housekeeping genes varies depending on mevalonate pathway inhibition in cancer cells

Expression of housekeeping genes varies depending on mevalonate pathway inhibition in cancer cells

Statins have anticancer effects and may be used as anticancer agents via drug repositioning. In reverse transcription-quantitative polymerase chain reaction (RT-qPCR) assays, the internal reference gene must not be affected by any experimental conditions. As statins exert a wide range of effects on...

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Bibliographic Details
Main Authors: Nanami Irie, Katsuhiko Warita, Jiro Tashiro, Yaxuan Zhou, Takuro Ishikawa, Zoltán N. Oltvai, Tomoko Warita
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Heliyon
Subjects:
Mevalonate pathway
Cancer cells
Statins
Housekeeping genes
RT-qPCR
Optimal internal reference genes
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023052258

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http://www.sciencedirect.com/science/article/pii/S2405844023052258

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