Epigenetic activation of POTE genes in ovarian cancer

Epigenetic activation of POTE genes in ovarian cancer

The POTE gene family consists of 14 homologous genes localized to autosomal pericentromeres, and a sub-set of POTEs are cancer-testis antigen (CTA) genes. POTEs are over-expressed in epithelial ovarian cancer (EOC), including the high-grade serous subtype (HGSC), and expression of individual POTEs c...

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Bibliographic Details
Main Authors: Ashok Sharma, Mustafa Albahrani, Wa Zhang, Christina N. Kufel, Smitha R. James, Kunle Odunsi, David Klinkebiel, Adam R. Karpf
Format: Article
Language:English
Published: Taylor & Francis Group 2019-02-01
Series:Epigenetics
Subjects:
pote
ovarian cancer
high-grade serous ovarian cancer
dna hypomethylation
pericentromeres
line1
Online Access:http://dx.doi.org/10.1080/15592294.2019.1581590

Internet

http://dx.doi.org/10.1080/15592294.2019.1581590

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