Remote ischemic preconditioning protects against liver ischemia-reperfusion injury via heme oxygenase-1-induced autophagy.

Growing evidence has linked autophagy to a protective role of preconditioning in liver ischemia/reperfusion (IR). Heme oxygenase-1 (HO-1) is essential in limiting inflammation and preventing the apoptotic response to IR. We previously demonstrated that HO-1 is up-regulated in liver graft after remot...

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Bibliographic Details
Main Authors: Yun Wang, Jian Shen, Xuanxuan Xiong, Yonghua Xu, Hai Zhang, Changjun Huang, Yuan Tian, Chengyu Jiao, Xuehao Wang, Xiangcheng Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4051645?pdf=render