A New Topical Candidate in Acne Treatment: Characterization of the Meclozine Hydrochloride as an Anti-Inflammatory Compound from In Vitro to a Preliminary Clinical Study

A New Topical Candidate in Acne Treatment: Characterization of the Meclozine Hydrochloride as an Anti-Inflammatory Compound from In Vitro to a Preliminary Clinical Study

Acne is a chronic inflammatory multifactorial disease involving the anaerobic bacterium <i>Cutibacterium acnes</i> (<i>C. acnes</i>). Current acne treatments are associated with adverse effects, limiting treatment compliance and use. We showed that meclozine, an anti-histamin...

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Bibliographic Details
Main Authors: Philippe A. Grange, Guillaume Ollagnier, Laurianne Beauvais Remigereau, Carole Nicco, Constance Mayslich, Anne-Geneviève Marcelin, Vincent Calvez, Nicolas Dupin
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomedicines
Subjects:
acne
<i>C. acnes</i>
inflammation
meclozine
anti-histaminic
human testing
Online Access:https://www.mdpi.com/2227-9059/10/5/931

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https://www.mdpi.com/2227-9059/10/5/931

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