Changes in seam number and location induce holes within microtubules assembled from porcine brain tubulin and in Xenopus egg cytoplasmic extracts

Changes in seam number and location induce holes within microtubules assembled from porcine brain tubulin and in Xenopus egg cytoplasmic extracts

Microtubules are tubes of about 25 nm in diameter that are critically involved in a variety of cellular functions, including motility, compartmentalization, and division. They are considered as pseudo-helical polymers whose constituent αβ-tubulin heterodimers share lateral homotypic interactions, ex...

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Bibliographic Details
Main Authors: Charlotte Guyomar, Clément Bousquet, Siou Ku, John M Heumann, Gabriel Guilloux, Natacha Gaillard, Claire Heichette, Laurence Duchesne, Michel O Steinmetz, Romain Gibeaux, Denis Chrétien
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-12-01
Series:eLife
Subjects:
Xenopus laevis
egg cytoplasmic extracts
microtubule
sus scrofa domesticus
purified tubulin
Online Access:https://elifesciences.org/articles/83021

Internet

https://elifesciences.org/articles/83021

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