Predominant Distribution of the RNAi Machinery at Apical Adherens Junctions in Colonic Epithelia Is Disrupted in Cancer

The RNA interference (RNAi) machinery is an essential component of the cell, regulating miRNA biogenesis and function. RNAi complexes were thought to localize either in the nucleus, such as the microprocessor, or in the cytoplasm, such as the RNA-induced silencing complex (RISC). We recently reveale...

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Bibliographic Details
Main Authors: Joyce Nair-Menon, Amanda C. Daulagala, Dean M. Connor, Lauren Rutledge, Trevor Penix, Mary Catherine Bridges, Bridgette Wellslager, Demetri D. Spyropoulos, Cynthia D. Timmers, Ann-Marie Broome, Antonis Kourtidis
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/7/2559