GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway

GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway

Abstract Background Research has indicated that long-term sleep deprivation can lead to immune dysfunction and participate in the occurance and progression of tumors. However, the relationship between sleep deprivation and colon cancer remains unclear. This study explored the specific mechanism thro...

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Bibliographic Details
Main Authors: Haijun Bao, Zuojie Peng, Xukai Cheng, Chenxing Jian, Xianguo Li, Yongping Shi, Wenzhong Zhu, Yuan Hu, Mi Jiang, Jia Song, Feifei Fang, Jinhuang Chen, Xiaogang Shu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Sleep deprivation
GABA
Colon cancer cells
Macrophages
Exosomes
miRNA
Online Access:https://doi.org/10.1186/s13046-023-02921-9

Internet

https://doi.org/10.1186/s13046-023-02921-9

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