Induction of Toll-Like Receptor 3-Mediated Immunity during Gestation Inhibits Cortical Neurogenesis and Causes Behavioral Disturbances

ABSTRACT Maternal infection during pregnancy with a wide range of RNA and DNA viruses is associated with increased risk for schizophrenia and autism in their offspring. A common feature in these exposures is that virus replication induces innate immunity through interaction with Toll-like receptors...

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Bibliographic Details
Main Authors: Joari De Miranda, Kavitha Yaddanapudi, Mady Hornig, Gabriel Villar, Robert Serge, W. Ian Lipkin
Format: Article
Language:English
Published: American Society for Microbiology 2010-10-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00176-10