Cenobamate as add-on therapy for drug resistant epilepsies: effectiveness, drug to drug interactions and neuropsychological impact. What have we learned from real word evidence?

Cenobamate as add-on therapy for drug resistant epilepsies: effectiveness, drug to drug interactions and neuropsychological impact. What have we learned from real word evidence?

Background: Cenobamate (CNB) is an anti-seizure medication (ASM) approved in 2021 in Europe for adjunctive treatment of focal-onset seizures in adults who were not adequately controlled with at least two previous ASMs.Methods: seizure outcome, treatment-emergent adverse events, neuropsychological pr...

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Bibliographic Details
Main Authors: Nicola Pietrafusa, Giovanni Falcicchio, Emilio Russo, Simona Lattanzi, Bianca Goffredo, Raffaele Simeoli, Sara Cairoli, Tiziana Corsetti, Roberta Roberti, Marina De Tommaso, Federico Vigevano, Angela La Neve, Nicola Specchio
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Pharmacology
Subjects:
cenobamate
epilepsy
focal-onset seizures
drug-resistance
blood levels
neuropsychology
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1239152/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1239152/full

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