Small molecule anion carriers facilitate lactate transport in model liposomes and cells

Small molecule anion carriers facilitate lactate transport in model liposomes and cells

Summary: An excessive production of lactate by cancer cells fosters tumor growth and metastasis. Therefore, targeting lactate metabolism and transport offers a new therapeutic strategy against cancer, based on dependency of some cancer cells for lactate as energy fuel or as oncogenic signal. Herein...

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Bibliographic Details
Main Authors: Daniel Alonso-Carrillo, Alain Arias-Betancur, Israel Carreira-Barral, Pere Fontova, Vanessa Soto-Cerrato, María García-Valverde, Ricardo Pérez-Tomás, Roberto Quesada
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Natural sciences
Biological sciences
Biochemistry
Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223019752

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223019752

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