Cellular Models of Alpha-Synuclein Aggregation: What Have We Learned and Implications for Future Study

Cellular Models of Alpha-Synuclein Aggregation: What Have We Learned and Implications for Future Study

Alpha-synuclein’s role in diseases termed “synucleinopathies”, including Parkinson’s disease, has been well-documented. However, after over 25 years of research, we still do not fully understand the alpha-synuclein protein and its role in disease. In vitro cellular models are some of the most powerf...

Full description

Bibliographic Details
Main Authors: Katrina Albert, Sara Kälvälä, Vili Hakosalo, Valtteri Syvänen, Patryk Krupa, Jonna Niskanen, Sanni Peltonen, Tuuli-Maria Sonninen, Šárka Lehtonen
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomedicines
Subjects:
alpha-synuclein
SH-SY5Y
hiPSCs
organoid
aggregation
synucleinopathy
Online Access:https://www.mdpi.com/2227-9059/10/10/2649

Internet

https://www.mdpi.com/2227-9059/10/10/2649

Similar Items