Heterotrophic Production of Omega-3 Long-Chain Polyunsaturated Fatty Acids by Trophically Converted Marine Diatom Phaeodactylum tricornutum

We have created via metabolic engineering a heterotrophic strain of Phaeodactylum tricornutum that accumulates enhanced levels of the high value omega-3 long chain polyunsaturated fatty acid (LC-PUFAs) docosahexaenoic acid (DHA). This was achieved by generation of transgenic strains in which the Δ5-...

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Bibliographic Details
Main Authors: Mary L. Hamilton, Stephen Powers, Johnathan A. Napier, Olga Sayanova
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/14/3/53