Abnormality in GABAergic postsynaptic transmission associated with anxiety in Bronx waltzer mice with an Srrm4 mutation

Abnormality in GABAergic postsynaptic transmission associated with anxiety in Bronx waltzer mice with an Srrm4 mutation

The homozygous Bronx waltzer (bv) mouse, which shows hearing impairment, also exhibits anxiety accompanied by a reduction in cortical parvalbumin (PV)-positive GABAergic interneurons. Recently, a mutation in splicing factor Ser/Arg repetitive matrix 4 (Srrm4) was found in bv mice. However, the cellu...

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Bibliographic Details
Main Authors: Yuka Shirakawa, Heng Li, Yuki Inoue, Hitomi Izumi, Yoshimi Kaga, Yu-ichi Goto, Ken Inoue, Masumi Inagaki
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:IBRO Neuroscience Reports
Subjects:
Anxiety
GABAergic interneuron
Parvalbumin
Srrm4
Bronx waltzer mouse
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242123022911

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http://www.sciencedirect.com/science/article/pii/S2667242123022911

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