In Vitro Metabolic Fate of the Synthetic Cannabinoid Receptor Agonists QMPSB and QMPCB (SGT-11) Including Isozyme Mapping and Esterase Activity

Quinolin-8-yl 4-methyl-3-(piperidine-1-sulfonyl)benzoate (QMPSB) and quinolin-8-yl 4-methyl-3-(piperidine-1-carbonyl)benzoate (QMPCB, SGT-11) are synthetic cannabinoid receptor agonists (SCRAs). Knowing their metabolic fate is crucial for the identification of toxicological screening targets and to...

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Bibliographic Details
Main Authors: Matthias J. Richter, Lea Wagmann, Tanja M. Gampfer, Simon D. Brandt, Markus R. Meyer
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/8/509